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Recombinant Human RCAN2 Protein

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Summary
Product Discontinued
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    • Catalog Number
      H00010231-P01
    • Availability
      Product Discontinued

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Recombinant Human RCAN2 Protein Summary

Description
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-225 of Human DSCR1L1 full-length ORF

Source: Wheat Germ (in vitro)

Amino Acid Sequence:MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTYDDCVTFQLFKSFRRVRINFSNPKSAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWQPINDATPVLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDIEEEEDPKTSPKPKIIQTRRPGLPPSVSNWAACSFSIIAVSSLSCFFPLLFVKKNCL
Preparation
Method
in vitro wheat germ expression system
Protein/Peptide Type
Recombinant Protein
Gene
RCAN2

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
Application Notes
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human RCAN2 Protein

  • Calcipressin 2 (Thyroid hormone-responsive protein ZAKI-4) (Down syndromecandidate region 1-like 1) (Myocyte-enriched calcineurin interacting protein2) (MCIP2)
  • calcipressin-2
  • Down syndrome candidate region 1-like 1
  • Down syndrome critical region gene 1-like 1
  • DSCR1L1MCIP2ZAKI4RCN2
  • hRCN2
  • Myocyte-enriched calcineurin-interacting protein 2
  • regulator of calcineurin 2CSP2
  • thyroid hormone-responsive (skin fibroblasts)
  • Thyroid hormone-responsive protein ZAKI-4
  • ZAKI-4

Background

Calcipressin-2, also known as RCAN2, plays a key role in many physiological procedures. Expressed in fibroblasts, heart, brain, liver, and skeletal muscle, RCAN2 prevents calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Translocation of the transcription factor NFATC1 can also be attributed to the binding of calcineurin A. Further research indicates that RCAN could also play a role in endothelial cell function, angiogenesis and central nervous system development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RCAN2