Recombinant Human D4-GDI/RhoGDI2 Protein

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-99668
    • Availability
      Product Discontinued

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Recombinant Human D4-GDI/RhoGDI2 Protein Summary

Description
Recombinant protein for Human D4-GDI/RhoGDI2

Source:E. coli
Amino Acid Sequence:(NM_004309)

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
ARHGDIB
Purity
>90%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% Glycerol.
Concentration
0.1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human D4-GDI/RhoGDI2 Protein

  • ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
  • D4
  • GDIA2
  • GDID4
  • LYGDI
  • Ly-GDI
  • RAP1GN1
  • RhoGDI2

Background

D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol ARHGDIB