Recombinant Human BMPR-IB/ALK-6 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00000658-G01
    • Availability
      Product Discontinued

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Recombinant Human BMPR-IB/ALK-6 Protein Summary

Protein/Peptide Type
Recombinant Protein
Gene
BMPR1B

Applications/Dilutions

Dilutions
  • Immunoaffinity Purification
Application Notes
In Vitro Wheat Germ System + Liposome Technology offers significant advantages over commonly used protein expression platforms:

Higher Yield
Greater Stability
High Expression Success Rate
Native Protein Conformation

This protein has not yet been tested for use in functional studies and/or compound screening.
All experiments requiring biological activity of the protein will not be backed by the Novus Guarantee or be eligible for the Innovator's Reward™ and must be undertaken at the customer's own risk.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Preservative
No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human BMPR-IB/ALK-6 Protein

  • activin receptor-like kinase 6
  • ALK-6
  • ALK6CDw293
  • BMP type-1B receptor
  • BMPR1B
  • BMPR-1B
  • BMPRIB
  • BMPR-IB
  • bone morphogenetic protein receptor type-1B
  • bone morphogenetic protein receptor, type IB
  • CDw293 antigen
  • CDw293
  • EC 2.7.11
  • EC 2.7.11.30
  • serine/threonine receptor kinase

Background

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol BMPR1B