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Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi

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Summary
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    • Catalog Number
      H00001134-R01
    • Availability
      Product Discontinued

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Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi Summary

Specificity
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) (CHRNA1), mRNA
Gene
CHRNA1

Applications/Dilutions

Dilutions
  • RNA Inhibition
  • RNAi sequence position
Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
DEPC-treated Water

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi

  • acetylcholine receptor subunit alpha
  • ACHRA
  • ACHRD
  • CHNRA
  • cholinergic receptor, nicotinic, alpha 1 (muscle)
  • CHRNA
  • CHRNA1
  • CMS2A
  • FCCMS
  • nAChR alpha 1
  • nAchRa1
  • Nicotinic Acetylcholine R alpha 1
  • Nicotinic Acetylcholine Ra1
  • nicotinic acetylcholine receptor alpha subunit
  • nicotinic cholinergic receptor alpha 1
  • nicotinic, alpha polypeptide 1 (muscle)
  • SCCMS

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi’s unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Publications for Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi (H00001134-R01) (0)

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Product General Protocols

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FAQs for Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi (H00001134-R01). (Showing 1 - 1 of 1 FAQ).

  1. I am looking to buy antibodies against most of the nicotinic receptor subunits for WB and IHC application. Could you please indicate which of your antibodies have been used by other researchers and provide publications showing their use? Thanks.
    • A list of our antibodies directed against he nicotinic acetylcholine receptors can be found here. Any products with publications will be indicated on the search page and can be found under the publications tab on the individual product's datasheet. Furthermore, we guarantee all of our products for the applications and species list on the datasheet. This should help narrow down your search.

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Bioinformatics

Gene Symbol CHRNA1