Gene Symbol | BLMH |
---|---|
Entrez Gene | 642 |
Alt Symbol | BH, BMH |
Species | Human |
Gene Type | protein-coding |
Description | bleomycin hydrolase |
Other Description | BLM hydrolase |
Swissprots | B2R796 Q9UER9 Q53F86 Q13867 |
Accessions | CAA74767 EAW51224 Q13867 AF091082 AAC72951 AI283058 AK057600 AK223403 BAD97123 AK301948 BAG63365 AK312896 BAG35743 BC003616 AAH03616 BG471412 BT007018 AAP35664 DC346179 X92106 CAA63078 NM_000386 NP_000377 |
Function | The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity. {ECO:0000250}. |
Subcellular Location | Cytoplasm. |