NME8

Gene Symbol NME8
Entrez Gene 51314
Alt Symbol CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2
Species Human
Gene Type protein-coding
Description NME/NM23 family member 8
Other Description sperm-specific thioredoxin 2|spermatid-specific thioredoxin-2|thioredoxin domain containing 3 (spermatozoa)|thioredoxin domain-containing protein 3
Swissprots Q8N427 Q9NZH1
Accessions EAW94083 EAW94084 Q8N427 AF202051 AAF20909 AF305596 AAN04258 AK313599 BAG36365 BC036816 AAH36816 JF432242 ADZ15459 NM_016616 NP_057700
Function Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11737268}.
Tissue Specificity Testis-specific. Expressed only in primary spermatocytes and round spermatids. {ECO:0000269|PubMed:11737268}.

Sptrx-2 CRISPR/Cas9 KO Plasmid (h) - sc-408227 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 HDR Plasmid (h) - sc-408227-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 Double Nickase Plasmid (h) - sc-408227-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 Double Nickase Plasmid (h2) - sc-408227-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 CRISPR Activation Plasmid (h) - sc-408227-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 CRISPR Activation Plasmid (h2) - sc-408227-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 Lentiviral Activation Particles (h) - sc-408227-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 Lentiviral Activation Particles (h2) - sc-408227-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sptrx-2 siRNA (h) - sc-89740 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sptrx-2 shRNA Plasmid (h) - sc-89740-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sptrx-2 shRNA (h) Lentiviral Particles - sc-89740-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TXNDC3 RNAi - H00051314-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU144321 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK2395 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2394 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2396 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN22308 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22308 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01562 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01562

NME8 siRNA (Human) - CRH9691 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TXNDC3 (NM_016616.4) - SHH438272 from Creative biogene

Category siRNA
Species Reactivities Human

NME8 shRNA Plasmid (Human) - CHH9691 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NME8 miRNA 3'UTR clone - MiUTR4H-TG09535 from Creative biogene

Species Reactivities Human
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