DCTPP1

Gene Symbol	DCTPP1
Entrez Gene	79077
Alt Symbol	CDA03, RS21C6, XTP3TPA
Species	Human
Gene Type	protein-coding
Description	dCTP pyrophosphatase 1
Other Description	XTP3-transactivated gene A protein|XTP3-transactivated protein A|dCTPase 1|deoxycytidine-triphosphatase 1
Swissprots	Q9H773
Accessions	EAW52247 Q9H773 AF210430 AAK48422 AF212242 AAK14927 AK024843 BAB15025 AY453409 AAR26724 BC001344 AAH01344 CR457335 CAG33616 NM_024096 NP_077001
Function	Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non- canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Top Pathways	Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

XTP3TPA CRISPR/Cas9 KO Plasmid (h) - sc-407430 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA HDR Plasmid (h) - sc-407430-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA Double Nickase Plasmid (h) - sc-407430-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA Double Nickase Plasmid (h2) - sc-407430-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA CRISPR Activation Plasmid (h) - sc-407430-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA CRISPR Activation Plasmid (h2) - sc-407430-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA Lentiviral Activation Particles (h) - sc-407430-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA Lentiviral Activation Particles (h2) - sc-407430-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA siRNA (h) - sc-93076 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

XTP3TPA shRNA Plasmid (h) - sc-93076-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

XTP3TPA shRNA (h) Lentiviral Particles - sc-93076-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU117691 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU042641 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7009 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7009 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04510 from Sigma-Aldrich Category miRNA

DCTPP1 siRNA (Human) - CRJ2295 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DCTPP1 - MBS8221865 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

XTP3TPA CRISPR/Cas9 KO Plasmid (h2) - sc-407430-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

XTP3TPA HDR Plasmid (h2) - sc-407430-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human DCTPP1 (NM_024096.1) - SHH275429 from Creative biogene Category siRNA Species Reactivities Human

Human DCTPP1 siRNA - orb272796 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DCTPP1 shRNA Plasmid (Human) - CHJ2295 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

DCTPP1 miRNA 3'UTR clone - MiUTR1H-11327 from Creative biogene Species Reactivities Human

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