CCNB1IP1

Gene Symbol	CCNB1IP1
Entrez Gene	57820
Alt Symbol	C14orf18, HEI10
Species	Human
Gene Type	protein-coding
Description	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase CCNB1IP1|human enhancer of invasion 10
Swissprots	Q9NPC3
Accessions	CAI93603 EAW66479 Q9NPC3 AA101731 AF216381 AAF36386 AI301662 AK026233 BAB15403 AK225253 AK225451 AK226037 AK309183 AL161994 CAB82326 AM393093 CAL37971 AM393651 CAL38527 BC000369 AAH00369 BC001218 AAH01218 BC004435 AAH04435 BI763317 BI771433 BI917081 BM741413 BX161423 CAD61896 BX161424 CAD61897 BX247978 CAD62312 BX334446 CB113193 DB029392 NM_182851 NM_021178 NP_067001 NM_182849 NP_878269 NM_182852 NP_878272
Function	Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome. Note=Associates to the synaptonemal complex.
Tissue Specificity	Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung. {ECO:0000269|PubMed:12612082}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HEI10 (Q-16) - sc-74659 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

HEI10 (W-15) - sc-74661 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-CCNB1IP1 antibody - ab75110 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 antibody - ab71977 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-CCNB1IP1 antibody [2114C2a] - ab84850 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2114C2a

Anti-CCNB1IP1 antibody [4H3] - ab118999 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4H3

Anti-CCNB1IP1 antibody - Aminoterminal end - ab171035 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 antibody - C-terminal - ab199862 from Abcam Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (clone 4H3) - LS-C337323 from LifeSpan Bioscience Prices $350.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4H3

Anti-CCNB1IP1 Antibody - LS-C125426 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-CCNB1IP1 Antibody (clone 2114C2a) - LS-C184728 from LifeSpan Bioscience Prices $335.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2114C2a

Anti-CCNB1IP1 Antibody (C-Terminus, AP) - LS-C221681 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus, APC) - LS-C221682 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus, Biotin) - LS-C221683 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus, FITC) - LS-C221684 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (N-Terminus) - LS-C170291 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus, Azide-free, HRP) - LS-C221685 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (aa201-250) - LS-C119927 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus, PE) - LS-C221686 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody - LS-C306782 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-CCNB1IP1 Antibody - LS-C309763 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (C-Terminus) - LS-C320101 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CCNB1IP1 Antibody (clone 2114C2a) - LS-C342760 from LifeSpan Bioscience Prices $375.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2114C2a

Anti-CCNB1IP1 Antibody (aa199-228) - LS-C168463 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

CCNB1IP1 Antibody (4H3) - NBP2-00600 from Novus Biologicals Prices $379.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4H3

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