Gene Symbol | TFDP1 |
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Entrez Gene | 7027 |
Alt Symbol | DP1, DRTF1, Dp-1 |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor Dp-1 |
Other Description | DRTF1-polypeptide 1|E2F dimerization partner 1|E2F-related transcription factor |
Swissprots | Q5JSB4 Q14186 B4DLQ9 Q8IZL5 |
Accessions | AAN46090 EAX09216 EAX09217 EAX09218 EAX09219 Q14186 AK297114 BAG59621 AK298521 BAH12805 AK310401 AK313742 BC011685 AAH11685 BC036601 CD623680 DQ589756 DQ892865 ABM83791 DQ896114 ABM87113 L23959 AAA58440 XM_005268326 XP_005268383 XM_005268327 XP_005268384 XM_005268328 XP_005268385 XM_005268330 XP_005268387 XM_005268331 XP_005268388 XM_011537518 XP_011535820 XM_011537519 XP_011535821 XM_011537520 XP_011535822 NM_007111 NP_009042 NR_026580 |
Function | Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000269|PubMed:20176812}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart. |
Top Pathways | Cell cycle, TGF-beta signaling pathway |
Human DP1 full length protein - ab159683 from Abcam
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Human DP1 protein fragment - ab159684 from Abcam
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Recombinant Human DP1 Protein - H00007027-Q01 from Novus Biologicals
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Recombinant Human DP1 Protein - H00007027-P01 from Novus Biologicals
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TFDP1 Blocking Peptide - 33R-8314 from Fitzgerald
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Tfdp1 Blocking Peptide - 33R-6777 from Fitzgerald
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TFDP1 Blocking Peptide - abx063341 from Abbexa
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TFDP1 - H00007027-P01 from Acris Antibodies
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TFDP1 - H00007027-Q01-10 from Acris Antibodies
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TFDP1 - H00007027-Q01-25 from Acris Antibodies
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TFDP1 fusion protein - Ag1511 from Proteintech Group
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Recombinant Human TFDP1, GST-tagged - TFDP1-3198H from Creative Biomart
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TFDP1 Blocking Peptide - CBP2147 from Cohesion Biosciences
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TFDP1 (V393) Peptide - BS1093P from Bioworld Technology
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Recombinant Human Transcription factor Dp-1(TFDP1) - CSB-YP023424HU CSB-EP023424HU CSB-BP023424HU CSB-MP023424HU from Cusabio
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TFDP1 Protein - abx165181 from Abbexa
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Recombinant Transcription Factor Dp1 (TFDP1) - RPM355Hu01 from Uscn Life Science Inc.
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TFDP1 (transcript variant 1) - TP303986 from Acris Antibodies
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TFDP1-Blocking-Peptide-N-Term - BP21890a from Abgent, a WuXi AppTec company
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TFDP1 Peptide, Human - M34GP15842H from Creative Peptides
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TFDP1 Recombinant Protein (OPCD07335) - OPCD07335 from Aviva Systems Biology
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DP1 Recombinant Protein Antigen - NBP2-57051PEP from Novus Biologicals
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DP1 Recombinant Protein Antigen - NBP2-55135PEP from Novus Biologicals
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TFDP1 peptide - orb218010 from Biorbyt
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