INSIG2

Gene Symbol INSIG2
Entrez Gene 51141
Alt Symbol -
Species Human
Gene Type protein-coding
Description insulin induced gene 2
Other Description INSIG-2|INSIG2 membrane protein|insulin induced protein 2|insulin-induced gene 2 protein
Swissprots Q9Y5U4 Q8TBI8 A8K5W8
Accessions AAX93280 EAW95199 EAW95200 Q9Y5U4 AF125392 AAD43048 AF527632 AAN28333 AK021692 AK291433 BAF84122 AK298599 BAG60785 AL080184 BC022475 AAH22475 BX647805 XM_005263690 XP_005263747 XM_011511292 XP_011509594 NM_016133 NP_057217
Function Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR. {ECO:0000269|PubMed:12242332, ECO:0000269|PubMed:16606821}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12242332}; Multi-pass membrane protein {ECO:0000269|PubMed:12242332}.

INSIG-2 (H-40) - sc-66936 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
INSIG-2 (H-40): sc-66936. Western blot analysis of INSIG-2 expression in mouse liver tissue extract.

INSIG-2 (R-15) - sc-34823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
INSIG-2 (R-15): sc-34823. Western blot analysis of INSIG-2 expression in untreated (A) and insulin-induced (B) Hep G2 whole cell lysates and rat liver tissue extract (C).

INSIG-2 (A-12) - sc-34821 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
INSIG-2 (A-12): sc-34821. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lower stomach tissue showing cytoplasmic staining of glandular cells.

Anti-Insig2 antibody - ab86415 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Insig2 antibody (ab86415) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal muscle lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Insig2 antibody - ab198247 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue labeling Insig2 using ab198247 at a 1/30 dilution.

Anti-Insig2 antibody - ab86351 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Insig2 antibody (ab86351) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-INSIG2 Antibody (N-Terminus) - LS-C101824 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
INSIG2 antibody LS-C101824 Western blot of Fetal Brain lysate.

INSIG-2 Antibody - NBP1-60007 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSIG-2 Antibody - NBP1-59687 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INSIG-2 Antibody [NBP1-59687] - Sample Type: 721_B Antibody Dilution: 1.0 ug/ml INSIG2 is supported by BioGPS gene expression data to be expressed in 721_B

Insig2 Polyclonal Antibody - bs-6625R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-INSIG2, (N-terminal) antibody produced in rabbit - SAB2103103 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-INSIG2, antibody produced in rabbit: <B>Cat. No. SAB2103103</B>: Immunoblotting analysis of INSIG2 in fetal brain tissue lysate with INSIG2 anitbody at 1 μg/mL.

Anti-INSIG2 antibody produced in rabbit - SAB4300996 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSIG2 antibody - N-terminal region (ARP40165_P050) - ARP40165_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSIG1 antibody - middle region (ARP40166_P050) - ARP40166_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INSIG1 antibody, Internal - GTX47434 from GeneTex

Prices $299.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-INSIG1 antibody, Internal used in Western blot. GTX47434

INSIG2 antibody, N-term - GTX47435 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

Anti -INSIG2 (Insulin-induced Gene 2 Protein, INSIG-2, INSIG2) - 223632 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

INSIG1 antibody - 70R-6594 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

INSIG2 antibody - 70R-6929 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

INSIG2 antibody - 24766-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human liver tissue slide using 24766-1-AP( INSIG2 Antibody) at dilution of 1:50 (under 10x lens)

INSIG1 Antibody - 25-589 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

INSIG2 Antibody - 25-588 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Brain at 0.2-1 ug/ml.

INSIG2 antibody - 24766-1-AP from Proteintech Group

Prices $279.00
Sizes con: 60 μg/150μl
Host Rabbit
Clonality Polyclonal
rat liver tissue were subjected to SDS PAGE followed by western blot with 24766-1-AP( INSIG2 Antibody) at dilution of 1:1000

INSIG2 Antibody - 36556 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36556 at dilution 1/30.

INSIG2 Antibody - GWB-MN344B from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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