Gene Symbol | EIF1AY |
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Entrez Gene | 9086 |
Alt Symbol | eIF-4C |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 1A, Y-linked |
Other Description | eIF-1A Y isoform|eukaryotic translation initiation factor 1A, Y chromosome|eukaryotic translation initiation factor 1A, Y-chromosomal|eukaryotic translation initiation factor 4C |
Swissprots | Q9BS77 O14602 |
Accessions | CCQ43273 EAX11716 O14602 AF000987 AAC51834 AK127664 BC005248 AAH05248 BF694967 BG499107 BP331805 BT007201 AAP35865 DQ786267 DQ890576 ABM92193 DQ893736 ABM84662 NM_001278612 NP_001265541 NM_004681 NP_004672 |
Function | Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | RNA transport |
eIF1AY CRISPR/Cas9 KO Plasmid (h) - sc-411241 from Santa Cruz Biotechnology
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eIF1AY HDR Plasmid (h) - sc-411241-HDR from Santa Cruz Biotechnology
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eIF1AY Double Nickase Plasmid (h) - sc-411241-NIC from Santa Cruz Biotechnology
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eIF1AY Double Nickase Plasmid (h2) - sc-411241-NIC-2 from Santa Cruz Biotechnology
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eIF1AY CRISPR Activation Plasmid (h) - sc-411241-ACT from Santa Cruz Biotechnology
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eIF1AY CRISPR Activation Plasmid (h2) - sc-411241-ACT-2 from Santa Cruz Biotechnology
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eIF1AY Lentiviral Activation Particles (h) - sc-411241-LAC from Santa Cruz Biotechnology
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eIF1AY Lentiviral Activation Particles (h2) - sc-411241-LAC-2 from Santa Cruz Biotechnology
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eIF1AY siRNA (h) - sc-91551 from Santa Cruz Biotechnology
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eIF1AY shRNA Plasmid (h) - sc-91551-SH from Santa Cruz Biotechnology
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eIF1AY shRNA (h) Lentiviral Particles - sc-91551-V from Santa Cruz Biotechnology
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EIF1AY RNAi - H00009086-R01 from Novus Biologicals
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MISSION® esiRNA - EHU128841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7738 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7738 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06543 from Sigma-Aldrich
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EIF1AY siRNA (Human) - CRH6001 from Cohesion Biosciences
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EIF1AY - MBS8201286 from MyBioSource
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shRNA set against Human Eif1a (NM_004681.2) - SHH284141 from Creative biogene
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shRNA set against Human EIF1AY(NM_004681.2) - SHH028253 from Creative biogene
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Human EIF1AY siRNA - orb266503 from Biorbyt
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EIF1AY shRNA Plasmid (Human) - CHH6001 from Cohesion Biosciences
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EIF1AY miRNA 3'UTR clone - MiUTR1H-03152 from Creative biogene
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