NELFB

Gene Symbol	NELFB
Entrez Gene	25920
Alt Symbol	COBRA1, NELF-B
Species	Human
Gene Type	protein-coding
Description	negative elongation factor complex member B
Other Description	cofactor of BRCA1|negative elongation factor B|negative elongation factor protein B
Swissprots	Q8WX92 Q96EW5 Q9Y3W0 Q9ULN8 Q9H9R4 A2BFA3
Accessions	EAW88377 EAW88378 Q8WX92 AB033008 BAA86496 AF464935 AAL69965 AK022651 BAB14157 AK091056 BAG52272 AL050280 CAB43381 AM393289 CAL38167 BC011892 AAH11892 BC019029 DA210427 NM_015456 NP_056271
Function	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12612062}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11739404}.
Tissue Specificity	Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human COBRA1 peptide - ab48335 from Abcam Category Peptide

Human COBRA1 protein fragment - ab132528 from Abcam Category Protein Source Wheat germ Species Human

NELFB / COBRA1 Antibody Blocking Peptide - LS-E3568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human COBRA1 Protein - H00025920-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

COBRA1-Antibody-Center-Blocking-Peptide - BP14765c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Negative elongation factor B (OPCA00521) - OPCA00521 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human COBRA1 protein - orb245187 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NELF-B - H00025920-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NELF-B - H00025920-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NELF-B fusion protein - ag9599 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NELF-B fusion protein - ag9237 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NELFB, GST-tagged - NELFB-1260H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant human Negative elongation factor B protein - CSB-EP037654h CSB-BP037654h CSB-MP037654h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Negative elongation factor B(COBRA1) - CSB-YP845164HU CSB-EP845164HU CSB-BP845164HU CSB-MP845164HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Negative elongation factor B(NELFB),partial - CSB-RP037654h from Cusabio Category Protein Source E.coli Species Human

Negative elongation factor B - RPC140927 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

NELF-B Protein - abx164892 from Abbexa Category Protein Species Human, Mouse, Rat

NELF-B - TP313518 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COBRA1 Recombinant Protein Antigen - NBP1-82924PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

COBRA1 Peptide, Human - M34GP03421H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant human Negative elongation factor B - AP71830 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Negative elongation factor B, Recombinant Protein - MBS9421660 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Negative elongation factor B, Recombinant Protein - MBS717301 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli

Negative elongation factor B (COBRA1), Recombinant Protein - MBS1482044 from MyBioSource Category Protein Prices $1,380.00, $1,380.00, $1,600.00, $1,600.00, $2,300.00, $2,300.00, $2,740.00, $2,740.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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