DBF4

Gene Symbol	DBF4
Entrez Gene	10926
Alt Symbol	ASK, CHIF, DBF4A, ZDBF1
Species	Human
Gene Type	protein-coding
Description	DBF4 zinc finger
Other Description	DBF4 homolog\|DBF4 zinc finger A\|DBF4-type zinc finger-containing protein 1\|activator of S phase kinase\|chiffon homolog A\|protein DBF4 homolog A\|zinc finger, DBF-type containing 1
Swissprots	A8K954 Q75N01 Q9UBU7 Q75MS6 A4D1D8 Q9Y2M6 O75226
Accessions	AAS07418 AAS07442 EAL24170 EAW76930 EAW76931 EAW76932 Q9UBU7 AB028069 BAA78326 AB028070 BAA78327 AF160249 AAD41911 AF160876 AAD45357 AK022969 BAG51144 AK292569 BAF85258 AK302010 BAG63412 AK303175 BAH13912 BC014909 BC022811 BC035632 BC036045 AAH36045 BC047693 AAH47693 XM_005250120 XP_005250177 XM_005250121 XP_005250178 XM_005250122 XP_005250179 XM_006715843 XP_006715906 XM_011515764 XP_011514066 XM_011515765 XP_011514067 XR_927343 NM_006716 NP_006707
Function	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. {ECO:0000269\|PubMed:10373557, ECO:0000269\|PubMed:10523313, ECO:0000269\|PubMed:17062569}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:10373557}.
Tissue Specificity	Highly expressed in testis and thymus. Expressed also in most cancer cells lines. {ECO:0000269\|PubMed:10373557}.
Top Pathways	Cell cycle

Dbf4 (H-300) - sc-11354 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Dbf4 (H-300): sc-11354. Western blot analysis of Dbf4 expression in Sol8 (A), PC-3 (B) and SW480 (C) nuclear extracts.

Dbf4 (K-15) - sc-5702 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dbf4 (N-15) - sc-5699 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-DBF4 antibody - ab70134 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-DBF4 antibody (ab70134) at 1/500 dilutionLane 1 : NIH3T3 cell extracts treated with H2O2 (100µM, 30mins) at 5 µgLane 2 : COS7 cell extracts treated with PMA (125mg/ml, 30mins)Lane 3 : NIH3T3 cell extracts treated with H2O2 (100µM, 30mins) and PMA (125mg/ml, 30mins) with immunising peptide at 5 µg

Anti-DBF4 antibody - ab56813 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

BDF4 antibody (ab56813) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human spleen.

Anti-DBF4 antibody - ab172687 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-DBF4 antibody (ab172687) at 1 µg/mlLane 1 : DBF4 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µg/ml per lane.SecondaryGoat anti-Rabbit IgG (H+L) HRP at 1/7500 dilutiondeveloped using the ECL technique

Anti-DBF4 antibody [EPR5635] - ab124707 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5635

All lanes : Anti-DBF4 antibody [EPR5635] (ab124707) at 1/10000 dilutionLane 1 : PC-3 cell lysatesLane 2 : Jurkat cell lysatesLane 3 : SW480 cell lysatesLane 4 : HepG2 cell lysatesLysates/proteins at 10 µg per lane.

Anti-DBF4 Antibody (clone 2047C4a) - LS-C184322 from LifeSpan Bioscience

Prices	$335.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2047C4a

Anti-DBF4 Antibody (aa100-150) - LS-C288479 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DBF4 Antibody - LS-C310083 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DBF4 Antibody (aa325-375) - LS-C288482 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DBF4 Antibody (aa1-349) - LS-C311625 from LifeSpan Bioscience

Prices	$250.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DBF4 Antibody (aa581-630) - LS-C151281 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DBF4 antibody Western Blot of Mouse Brain.

Anti-DBF4 Antibody (aa585-599) - LS-C139824 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

DBF4 antibody (1 ug/ml) staining of Mouse Testis lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DBF4 Antibody (Internal, clone EPR5635) - LS-C138747 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5635

Western blot analysis on (A) PC-3, (B) Jurkat, (C) SW480, and (D) HepG2 cell lysates using anti-DBF4 antibody.

Anti-DBF4 Antibody (Ile18) - LS-C176953 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Dbf4 (I18) pAb in extracts from NIH-3T3 treated with H2O2 100uM 30'.

Anti-DBF4 Antibody (clone 2047C4a) - LS-C342376 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2047C4a

Western blot analysis of immunized recombinant protein, using anti-DBF4 monoclonal antibody.

Anti-DBF4 Antibody (aa10-59) - LS-C119300 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from NIH-3T3 cells, treated with H2O2 100 uM 30', COS7 treated with PMA 125 ng/ml 30', using DBF4 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-DBF4 Antibody (clone 6G9) - LS-C133665 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6G9

Immunofluorescence of monoclonal antibody to DBF4 on HeLa cell. [antibody concentration 10 ug/ml].

Anti-DBF4 Antibody (aa325-375) - LS-C125433 from LifeSpan Bioscience

Prices	$545.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DBF4 Antibody - LS-C64525 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

DBF4 Antibody (6G9) - H00010926-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6G9

DBF4 Antibody - NBP2-33620 from Novus Biologicals

Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: DBF4 Antibody [NBP2-33620] - liver

DBF4 Antibody - NBP1-19618 from Novus Biologicals

Host	Rabbit
Clonality	Polyclonal

Western Blot: DBF4 Antibody [NBP1-19618] - DBF4 Antibody extracts from NIH-3T3 treated with H2O2 100uM 30'.

DBF4 Antibody - H00010926-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: DBF4 Antibody [H00010926-A01] - 4 polyclonal antibody (A01), Lot # 060614JCS1 Western Blot analysis of DBF4 expression in Jurkat ( Cat # L017V1 ).

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