Gene Symbol |
BCL2L10
|
Entrez Gene |
10017
|
Alt Symbol |
BCL-B, Boo, Diva, bcl2-L-10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
BCL2-like 10 (apoptosis facilitator)
|
Other Description |
anti-apoptotic protein NrH|apoptosis regulator Bcl-B|bcl-2-like protein 10|death inducer binding to vBcl-2 and Apaf-1
|
Swissprots |
Q3SX80 Q8TCS9 Q9HD36 Q52LQ9
|
Accessions |
CAD30221 EAW77435 Q9HD36 AF285092 AAG00503 AF326964 AAK48715 BC093826 AAH93826 BC093828 AAH93828 BC104442 AAI04443 BC104443 AAI04444 BC143227 BX119239 XM_005254103 XP_005254160 NM_001306168 NP_001293097 NM_020396 NP_065129
|
Function |
Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. {ECO:0000269|PubMed:11278245}.
|
Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:11593390}. Nucleus membrane {ECO:0000269|PubMed:11593390}.
|
Tissue Specificity |
Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney. {ECO:0000269|PubMed:11593390}.
|