CENPN

Gene Symbol CENPN
Entrez Gene 55839
Alt Symbol BM039, C16orf60, CENP-N, ICEN32
Species Human
Gene Type protein-coding
Description centromere protein N
Other Description interphase centromere complex protein 32
Swissprots D3DUK8 E7ES30 B3KN53 B4DJD1 E7ETS3 A8MZE6 Q9NZ83 Q96H22 C9JJM5 B4DPY7
Accessions EAW95553 EAW95554 EAW95555 EAW95556 Q96H22 AF217515 AAF67626 AK023669 BAG51215 AK026313 AK296024 BAG58793 AK298554 BAG60749 AW085187 BC007334 AAH07334 BC008972 AAH08972 BC039021 BQ013821 HY167728 HY363272 HY374758 XM_006721236 XP_006721299 NM_001100624 NP_001094094 NM_001100625 NP_001094095 NM_001270473 NP_001257402 NM_001270474 NP_001257403 NM_018455 NP_060925
Function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. {ECO:0000269|PubMed:16622419, ECO:0000269|PubMed:16716197, ECO:0000269|PubMed:18007590, ECO:0000269|PubMed:19543270}.
Subcellular Location Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. Kinetochore-bound levels decrease when cells enter mitosis and increase again when cells exit mitosis.

CENP-N (P-17) - sc-69152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CENP-N (P-17): sc-69152. Western blot analysis of CENP-N expression in HeLa nuclear extract.

CENP-N (S-16) - sc-69153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CENPN antibody - ab104296 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CENPN antibody (ab104296) at 1/50 dilution + MCF7 cell lysate at 35 µg

Anti-CENPN antibody - ab57660 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57660 BM039 antibody at 1ug/ml.

Anti-CENPN / CENP-N Antibody (clone 4A5-1C11) - LS-C306551 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A5-1C11

Anti-CENPN / CENP-N Antibody - LS-C309878 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CENPN / CENP-N Antibody - LS-C309879 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CENPN / CENP-N Antibody (clone 22F4) - LS-C179531 from LifeSpan Bioscience

Prices $380.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 22F4

Anti-CENPN / CENP-N Antibody (aa107-156) - LS-C135435 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CENPN antibody LS-C135435 Western blot of Jurkat lysate.

Anti-CENPN / CENP-N Antibody (aa309-339) - LS-C168671 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of CENPN Antibody in MCF-7 cell line lysates (35 ug/lane). CENPN (arrow) was detected using the purified antibody.

CENPN Antibody - NBP1-79664 from Novus Biologicals

Prices $139.00, $369.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

CENPN Antibody - H00055839-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CENPN Antibody [H00055839-D01] - Expression in transfected 293T cell line. Lane 1: CENPN transfected lysate(24.10 KDa). Lane 2: Non-transfected lysate.

CENPN Antibody (4A5-1C11) - H00055839-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A5-1C11

CENPN Antibody - H00055839-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CENPN Antibody [H00055839-D01P] - Analysis of CENPN expression in transfected 293T cell line by CENPN polyclonal antibody.Lane 1: CENPN transfected lysate(24.10 KDa).Lane 2: Non-transfected lysate.

Anti-CENPN antibody produced in rabbit - SAB1411083 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CENPN: <B>Cat. No. SAB1411083</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~24.1 kDa using CENPN transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-BM039 antibody produced in mouse - WH0055839M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A5-1C11
<B>Immunoblotting</B><BR/>Monoclonal Anti-BM039, <B>Cat. No. WH0055839M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~48.55 kDa using immunogen protein lysate.

CENPN antibody - middle region (ARP57258_P050) - ARP57258_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CENPN Antibody - C-terminal region (OAAB02327) - OAAB02327 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CENPN-Antibody-C-term - AP4913b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CENPN Antibody (C-term) (Cat. #AP4913b) in MCF-7 cell line lysates (35ug/lane).CENPN (arrow) was detected using the purified Pab.

CENPN antibody - 70R-9488 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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