| Gene Symbol |
NT5C3A
|
| Entrez Gene |
51251
|
| Alt Symbol |
NT5C3, P5'N-1, P5N-1, PN-I, POMP, PSN1, UMPH, UMPH1, cN-III, hUMP1, p36
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5'-nucleotidase, cytosolic IIIA
|
| Other Description |
5'-nucleotidase, cytosolic III|cytosolic 5'-nucleotidase 3|cytosolic 5'-nucleotidase 3A|lupin|pyrimidine 5'-nucleotidase 1|uridine 5'-monophosphate hydrolase 1
|
| Swissprots |
Q9UC45 B8ZZC4 B2RAA5 Q9UC43 Q9P0P5 Q7L3G6 Q6IPZ1 A8K253 Q6NXS6 Q9UC44 Q9UC42 Q9H0P0
|
| Accessions |
EAL24463 EAW94007 EAW94008 EAW94009 EAW94010 EAW94011 Q9H0P0 AA482595 AF151067 AAF36153 AF312735 AAG33630 AK290118 BAF82807 AK314109 BAG36802 AL136716 CAB66650 AM393138 CAL38016 AM393316 CAL38194 AM393481 CAL38358 AW339593 BC013292 AAH13292 BC015856 AAH15856 BC066914 AAH66914 BC071652 AAH71652 BF790086 CB127255 CB127877 CB137440 CR533518 CAG38549 DA975244 DB243020 DB346026 DQ892843 ABM83769 EU176737 ABW03538 N98231 XM_011515409 XP_011513711 NM_001002009 NP_001002009 NM_001002010 NP_001002010 NM_001166118 NP_001159590 NM_016489 NP_057573
|
| Function |
Can act both as nucleotidase and as phosphotransferase.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}.
|
| Tissue Specificity |
Isoform 1 and isoform 3 are expressed in reticulocytes and lymphocytes. Isoform 4 is expressed only in reticulocytes. {ECO:0000269|PubMed:11369620, ECO:0000269|PubMed:15238149}.
|
| Top Pathways |
Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism
|
![Western Blot: NT5C3 Overexpression Lysate (Adult Normal) [NBL1-13822] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NT5C3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2308_NT5C3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13822-img0002.jpg)