Gene Symbol | Ngf |
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Entrez Gene | 18049 |
Alt Symbol | Ngfb |
Species | Mouse |
Gene Type | protein-coding |
Description | nerve growth factor |
Other Description | beta-NGF|beta-nerve growth factor|nerve growth factor, beta |
Swissprots | Q6LDB7 Q63864 P01139 |
Accessions | AAA37686 AAA37687 EDL07614 EDL07615 P01139 AK144588 BAE25950 BC011123 BC156604 AAI56605 BF786523 BY334442 K01759 AAA39820 M14805 AAA39821 M35075 AAA39818 S62089 AAB26820 V00836 CAA24221 XM_006501108 XP_006501171 XM_006501109 XP_006501172 XM_006501110 XP_006501173 NM_001112698 NP_001106168 NM_013609 NP_038637 |
Function | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. {ECO:0000250|UniProtKB:P01138}. |
Subcellular Location | Secreted. |
Top Pathways | Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Inflammatory mediator regulation of TRP channels |
NGF (NGF30) - sc-32300 from Santa Cruz Biotechnology
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Anti-NGF antibody - ab150342 from Abcam
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Anti-Nerve Growth Factor Antibody - LS-C42053 from LifeSpan Bioscience
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Anti-Nerve Growth Factor Antibody - LS-C91075 from LifeSpan Bioscience
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Anti-Nerve Growth Factor Antibody - LS-C91076 from LifeSpan Bioscience
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beta-NGF Antibody - NBP2-36711 from Novus Biologicals
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beta-NGF Antibody - NBP2-36678 from Novus Biologicals
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mNGF-Antibody - AG1203 from Abgent, a WuXi AppTec company
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NGF antibody - GTX39581 from GeneTex
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NGF antibody - GTX39579 from GeneTex
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TrkA antibody (Tyr757) - 70R-32744 from Fitzgerald
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NGF antibody - PAB0755 from Acris Antibodies
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NGF antibody - PAB0756 from Acris Antibodies
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NGF antibody - PAB0757 from Acris Antibodies
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NGF antibody - PAB14337 from Acris Antibodies
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Recombinant Mouse β-NGF (carrier-free) - 598102 from Biolegend
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NGF Antibody - XG-6100 from ProSci
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NGF 2.5S Antibody - GWB-B58C0F from Genway Biotech
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Rabbit Anti-Nerve Growth Factor 2.5S Polyclonal antibody - CPBT-66524RN from Creative Diagnostics
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Anti-NGF polyclonal antibody - CPBT-66526SN from Creative Diagnostics
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Rabbit Anti-Mouse Nerve Growth Factor 2.5S Polyclonal antibody - CPBT-67998RM from Creative Diagnostics
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Magic™ Anti-NGF (aa 74-85-113-124) polyclonal antibody - DPABH-27900 from Creative Diagnostics
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NGF / NGFB Antibody, Rabbit PAb - 50385-RP01-200 from Sino Biological
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NGF / NGFB Antibody, Rabbit PAb, Antigen Affinity Purified - 50385-T16-50 from Sino Biological
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Anti-Ngf monoclonal antibody, clone OHG - DCABH-16197 from Creative Diagnostics
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