| Gene Symbol |
ptch2
|
| Entrez Gene |
30181
|
| Alt Symbol |
ptc-1, ptc1, ptch1
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
patched 2
|
| Other Description |
blowout|blw|etID309849.2|patched 1|protein patched homolog 1
|
| Swissprots |
Q98864
|
| Accessions |
Q98864 BC139606 AAI39607 X98883 CAA67386 XM_005163479 XP_005163536 NM_130988 NP_571063
|
| Function |
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Detected in embryonic presomitic mesoderm, neuroectoderm, tissue surrounding the notochord, ventral neural tube.
|
| Top Pathways |
Hedgehog signaling pathway
|