Gene Symbol | PXDNL |
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Entrez Gene | 137902 |
Alt Symbol | PMR1, PRM1, VPO2 |
Species | Human |
Gene Type | protein-coding |
Description | peroxidasin-like |
Other Description | cardiac peroxidase|cardiovascular peroxidase 2|peroxidasin homolog-like|peroxidasin-like protein|polysomal ribonuclease 1 homolog|vascular peroxidase 2 |
Swissprots | B6CGZ3 A1KZ92 Q96LH9 B5ME43 H0YBM9 Q6ZMR2 |
Accessions | A1KZ92 EAW86707 EAW86708 AI127081 AK058200 BAB71713 AK131524 BAD18663 AY877349 AAX70929 BC132813 DB337228 EU170240 ABX24517 HG501154 KJ545488 AHZ56584 XM_005251168 XP_005251225 XM_006716420 XP_006716483 XM_011517456 XP_011515758 XM_011517457 XP_011515759 XM_011517458 XP_011515760 XM_011517459 XP_011515761 XR_928757 NM_144651 NP_653252 |
Function | Isoform PMR1: Endonuclease selectively degrading some target mRNAs while they are engaged by translating ribosomes, among which albumin and beta-globin mRNAs. {ECO:0000269|PubMed:22543864}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | the 57 kDa isoform PMR1 is the only form detected at protein levels in human cell lines. {ECO:0000269|PubMed:22543864}. |
PXDNL CRISPR/Cas9 KO Plasmid (h) - sc-405231 from Santa Cruz Biotechnology
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PXDNL HDR Plasmid (h) - sc-405231-HDR from Santa Cruz Biotechnology
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PXDNL Double Nickase Plasmid (h) - sc-405231-NIC from Santa Cruz Biotechnology
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PXDNL Double Nickase Plasmid (h2) - sc-405231-NIC-2 from Santa Cruz Biotechnology
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PXDNL CRISPR Activation Plasmid (h) - sc-405231-ACT from Santa Cruz Biotechnology
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PXDNL CRISPR Activation Plasmid (h2) - sc-405231-ACT-2 from Santa Cruz Biotechnology
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PXDNL Lentiviral Activation Particles (h) - sc-405231-LAC from Santa Cruz Biotechnology
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PXDNL Lentiviral Activation Particles (h2) - sc-405231-LAC-2 from Santa Cruz Biotechnology
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PXDNL siRNA (h) - sc-77868 from Santa Cruz Biotechnology
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PXDNL shRNA Plasmid (h) - sc-77868-SH from Santa Cruz Biotechnology
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PXDNL shRNA (h) Lentiviral Particles - sc-77868-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU146231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17761 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02691 from Sigma-Aldrich
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PXDNL siRNA (Human) - CRJ5208 from Cohesion Biosciences
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shRNA set against Human PXDNL (NM_144651.4) - SHH387296 from Creative biogene
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Human PXDNL siRNA - orb275709 from Biorbyt
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PXDNL shRNA Plasmid (Human) - CHJ5208 from Cohesion Biosciences
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PXDNL miRNA 3'UTR clone - MiUTR1H-08512 from Creative biogene
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