| Gene Symbol |
RALGPS1
|
| Entrez Gene |
9649
|
| Alt Symbol |
RALGEF2, RALGPS1A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Ral GEF with PH domain and SH3 binding motif 1
|
| Other Description |
Ral guanine nucleotide exchange factor RalGPS1A|RalGEF 2|ral GEF with PH domain and SH3-binding motif 1|ral guanine nucleotide exchange factor 2|ralA exchange factor RalGPS1|ras-specific guanine nucleotide-releasing factor RalGPS1
|
| Swissprots |
Q5JUG5 E9PBQ5 Q5JS13 B4DR86 Q9NZ16 O15059 Q5JT60 Q5JT65 Q8N4S6 Q8N5H4 Q8WUV7
|
| Accessions |
EAW87645 EAW87646 EAW87647 EAW87648 Q5JS13 AB002349 BAA20808 AF221098 AAF65253 AK299149 BAG61198 BC019329 AAH19329 BC032372 AAH32372 BC033708 AAH33708 BX648170 BY797926 CB162049 CN266562 DB332662 DB521440 DR001330 XM_006717327 XP_006717390 XM_006717328 XP_006717391 XM_011519225 XP_011517527 XM_011519226 XP_011517528 XM_011519227 XP_011517529 XM_011519228 XP_011517530 XM_011519229 XP_011517531 XM_011519230 XP_011517532 XM_011519231 XP_011517533 XM_011519232 XP_011517534 XM_011519233 XP_011517535 XM_011519234 XP_011517536 XM_011519235 XP_011517537 XM_011519236 XP_011517538 XM_011519237 XP_011517539 XM_011519238 XP_011517540 XM_011519239 XP_011517541 XM_011519240 XP_011517542 XR_929879 NM_001190728 NP_001177657 NM_001190729 NP_001177658 NM_001190730 NP_001177659 NM_014636 NP_055451
|
| Function |
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. {ECO:0000250, ECO:0000269|PubMed:10747847, ECO:0000269|PubMed:10889189}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10889189}. Cell membrane {ECO:0000269|PubMed:10889189}. Note=Associates with membranes through the PH domain.
|
| Tissue Specificity |
Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. {ECO:0000269|PubMed:10747847, ECO:0000269|PubMed:10889189}.
|
