| Gene Symbol | ZFP36 |
|---|---|
| Entrez Gene | 282127 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | ZFP36 ring finger protein |
| Other Description | TIS11|TTP|tristetraprolin|tristetraproline|zfp-36|zinc finger protein 36 homolog|zinc finger protein 36, C3H type, homolog|zinc finger protein homologous to Zfp-36 in mouse |
| Swissprots | P53781 |
| Accessions | AAB05819 DAA19897 P53781 BC120043 AAI20044 NM_174493 NP_776918 |
| Function | mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules (By similarity). {ECO:0000250}. |
| Top Pathways | HTLV-I infection |
Tristetraprolin, ZFP36, Bovine, ELISA Kit - E5400b from ARP American Research Products
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zinc finger protein 36, C3H type, homolog (mouse) , ELISA Kit - MBS9341373 from MyBioSource
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Bovine ZFP36 ELISA Kit - E101589 from Biobool
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Tristetraprolin, ELISA Kit - MBS2883994 from MyBioSource
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Tristetraprolin (TTP/ZFP36), ELISA Kit - MBS2610132 from MyBioSource
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Tristetraprolin (ZFP36), ELISA Kit - MBS2610269 from MyBioSource
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