GRM8

Gene Symbol	GRM8
Entrez Gene	2918
Alt Symbol	GLUR8, GPRC1H, MGLUR8, mGlu8
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 8
Other Description	metabotropic glutamate receptor 8
Swissprots	O95945 B0M0L0 B0FZ74 Q6J165 O15493 O00222 A4D0Y3 Q3MIV9 O95946 Q52M02
Accessions	AAB46348 ABY59657 CAJ46924 CBJ21208 EAL24322 EAW83621 EAW83622 EAW83623 EAW83624 O00222 AJ236921 CAB36968 AJ236922 CAB36969 AK123053 AK290197 BAF82886 AK315203 AY608335 AAT37959 BC093725 AAH93725 BC101675 AAI01676 BC143344 BG202742 BG211606 EU432125 ABY87924 U92459 AAB51764 U95025 AAB72040 XM_006715938 XP_006716001 XM_011516091 XP_011514393 XM_011516092 XP_011514394 XM_011516093 XP_011514395 XM_011516094 XP_011514396 XM_011516095 XP_011514397 XM_011516096 XP_011514398 XM_011516097 XP_011514399 XM_011516098 XP_011514400 XM_011516099 XP_011514401 XM_011516100 XP_011514402 XM_011516101 XP_011514403 XM_011516102 XP_011514404 XM_011516103 XP_011514405 XM_011516104 XP_011514406 XM_011516105 XP_011514407 XM_011516106 XP_011514408 XM_011516107 XP_011514409 XM_011516108 XP_011514410 XM_011516109 XP_011514411 NM_000845 NP_000836 NM_001127323 NP_001120795 NR_028041
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:9473604}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Top Pathways	Glutamatergic synapse, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 8 protein fragment - ab114473 from Abcam Category Protein Source Wheat germ Species Human

GRM8 / MGLUR8 Antibody Blocking Peptide - LS-E2698 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM8 / MGLUR8 Antibody Blocking Peptide - LS-E4165 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM8 / MGLUR8 Antibody Blocking Peptide - LS-E29573 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM8 / MGLUR8 Antibody Blocking Peptide - LS-E29578 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM8 / MGLUR8 Antibody Blocking Peptide - LS-E29587 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human mGluR8 Protein - H00002918-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human mGluR8 Protein - H00002918-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

mGluR8 Peptide - P0614 from Novus Biologicals Category Peptide Species Human

GRM8-Antibody-C-term-Blocking-peptide - BP13777b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Metabotropic-Glutamate-Receptor-8-Antibody-C-term-Blocking-peptide - BP1641a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

mGLUR8 Blocking Peptide - abx062703 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey, Pig, Rabbit

mGluR8 / GRM8 - H00002918-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

mGluR8 / GRM8 (C-term) - H00002918-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR8 / GRM8 (C-term) - H00002918-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GRM8 fusion protein - Ag13011 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human GRM8 - GRM8-28274TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human GRM8, His-tagged - GRM8-13546H from Creative Biomart Category Protein Source E.coli Species Human

mGLUR8 Blocking Peptide - CBP1509 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey, Pig, Rabbit

mGluR-8 (Q871) Peptide - BS1148P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

mGluR8 Recombinant Protein Antigen - NBP2-14073PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GRM8 Peptide, Human - M34GP06680H from Creative Peptides Category Peptide Source Synthetic. Species Human

Metabotropic glutamate receptor 8 (GRM8), Recombinant Protein - MBS1034005 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GRM8 peptide - orb217372 from Biorbyt Category Peptide Species Human, Mouse, Rat, Monkey

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