Grm1

Gene Symbol Grm1
Entrez Gene 24414
Alt Symbol Gprc1a
Species Rat
Gene Type protein-coding
Description glutamate receptor, metabotropic 1
Other Description G protein coupled receptor family C group 1 member A|mGluR1|metabotropic glutamate receptor 1
Swissprots P23385
Accessions EDL93710 EDL93711 P23385 M61099 AAA19497 X57569 CAA40799 Y18809 CAB51054 Y18810 CAB51055 Y18811 CAB51056 Y18812 CAB51057 NM_001114330 NP_001107802 NM_017011 NP_058707
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. {ECO:0000269|PubMed:10945991, ECO:0000269|PubMed:1438218, ECO:0000269|PubMed:1656524, ECO:0000269|PubMed:1847995}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10945991}; Multi-pass membrane protein {ECO:0000269|PubMed:10945991}.
Tissue Specificity Predominantly expressed in cerebellar Purkinje cells, CA2-CA3 pyramidal cells of the hippocampus, and mitral and tufted cells of the olfactory bulb. {ECO:0000269|PubMed:1656524, ECO:0000269|PubMed:1847995}.
Top Pathways Glutamatergic synapse, Calcium signaling pathway, Long-term depression, Retrograde endocannabinoid signaling, Estrogen signaling pathway

metabotropic Glutamate Receptor 1a Antibody - NB300-123 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: metabotropic Glutamate Receptor 1a Antibody [NB300-123] - 10 ug of HEK 293 cells expression. As shown in the autoradiograph, the mGluR1a antibody is specific for the ~125k monomer and the ~250k dimer of mGluR1a (Lane A). The mGluR1a antibody shows no reactivity towards mGluR5 (Lane B).

Metabotropic-Glutamate-Receptor-1a-Antibody - AN1047 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the specific immunolabeling of the ~125k monomer and the ~250k dimer of mGluR1a. The mGluR1a antibody shows no reactivity toward mGluR5.

mGluR1-extracellular-Antibody - AG1263 from Abgent, a WuXi AppTec company

Prices $375.00, $475.00, $575.00
Sizes 25 µl, 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat brain lysate: 1. Anti-mGluR1 (extracellular) antibody (#AG1263), (1:200). 2. Anti-mGluR1 (extracellular) antibody, preincubated with the control peptide antigen.

mGluR1a antibody - GTX82654 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-Metabotropic Glutamate Receptor 1a antibody used in Western blot. GTX82654

mGluR1 antibody - GTX39713 from GeneTex

Prices $469.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

Metabotropic Glutamate Receptor 1a antibody - orb176536 from Biorbyt

Prices $400.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

Glutamate Receptor, Metabotropic 1 Antibody - abx112750 from Abbexa

Host Rabbit
Clonality Polyclonal

mGluR1a / GRM1a antibody - AP05198PU-N from Acris Antibodies

Prices $440.00
Sizes 10 blots
Host Rabbit
Clonality Polyclonal
Western blot analysis using mGluR1a receptor antibody on HEK-293 cell lysate.

mGluR1a / GRM1a (C-term) antibody - AP08691PU-N from Acris Antibodies

Prices $350.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Figure 1. Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the specific immunolabeling of the ~125k monomer and the ~250k dimer of mGluR1a. The mGluR1a antibody shows no reactivity toward mGluR5.

mGluR1a / GRM1a antibody - PAB9616 from Acris Antibodies

Prices $430.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Metabotropic Glutamate Receptor 1a Antibody - 50-101 from ProSci

Prices $350.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10µg of HEK 293 cells expressing mGluR1a and mGluR5 showing specific immunolabeling of the ~125k monomer and the ~250k dimer of mGluR1a.

mGluR1 Antibody - 253170 from ABBIOTEC

Prices $363.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rat Metabortropic Glutamate Receptor A1 Antibody - GWB-4C6AF6 from Genway Biotech

Prices $709.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM1 (aa 1115-1130) polyclonal antibody - CPBT-66129RR from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

mGluR1 Polyclonal Antibody - PA1-12753 from Thermo Fisher Scientific

Prices $399.00
Sizes 10 miniblots
Host Rabbit
Clonality Polyclonal

mGluR1/mGluR5 Polyclonal Antibody - PA1-12755 from Thermo Fisher Scientific

Prices $399.00
Sizes 10 miniblots
Host Rabbit
Clonality Polyclonal

mGluR1/mGluR5 Polyclonal Antibody - PA1-4663 from Thermo Fisher Scientific

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 µg of HEK 293 cells expression. As shown in the autoradiograph, the mGluR5/1a antibody recognizes both mGluR5 and mGluR1a labeling both the ~125 kDa monomer and the ~250 kDa dimers for both mGluRs.

Metabotropic Glutamate Receptor 1a, Polyclonal Antibody - MBS395551 from MyBioSource

Prices $430.00
Sizes 10 miniblots
Host Rabbit
Clonality Polyclonal

METABOTROPIC GLUTAMATE RECEPTOR 1a, Polyclonal Antibody - MBS224070 from MyBioSource

Prices $650.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Metabotropic Glutamate Receptor 1a, Polyclonal Antibody - MBS502157 from MyBioSource

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-mGluR1 Antibody - 07-617 from EMD Millipore

Prices $359.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

mGluR1 (extracellular) polyclonal antibody - BML-SA610-0050 from Enzo Life Sciences

Prices $345.00, $517.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

Metabotropic Glutamate Receptor 1a Antibody - AHP1871 from AbD Serotec

Prices $490.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRM1 Antibody - CSB-PA009931GA01HU from Cusabio

Host Rabbit

mGluR1 (extracellular) Antibody - WGA1270 from WuXi Biosciences

Prices $375.00, $475.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat brain lysate: 1. Anti-mGluR1 (extracellular) antibody (#WGA1270), (1:200). 2. Anti-mGluR1 (extracellular) antibody, preincubated with the control peptide antigen.
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