EIF2S2

Gene Symbol EIF2S2
Entrez Gene 8894
Alt Symbol EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
Other Description eukaryotic translation initiation factor 2 subunit 2|eukaryotic translation initiation factor 2 subunit beta|protein phosphatase 1, regulatory subunit 67
Swissprots Q9BVU0 P20042 Q9UJE4
Accessions AAD19864 EAW76284 EAW76285 EAW76286 P20042 AB208966 BAD92203 AB451237 BAG70051 AB451362 BAG70176 AK313025 BAG35860 BC000461 AAH00461 BC000934 AAH00934 BC007888 AAH07888 BC070316 BC107588 AAI07589 BT009795 AAP88797 BX648379 CR456734 CAG33015 DQ891005 ABM81931 DQ894184 ABM85110 M29536 AAA52383 XM_005260605 XP_005260662 NM_003908 NP_003899
Function eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Top Pathways RNA transport

eIF2β (C-1) - sc-133133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
eIF2β (C-1): sc-133133. Western blot analysis of eIF2β expression in 293 (A), KNRK (B), A-431 (C) and NIH/3T3 (D) whole cell lysates.

eIF2β (C-15) - sc-31888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
eIF2β (C-15): sc-31888. Western blot analysis of eIF2β expression in K-562 (A) and NIH/3T3 (B) whole cell lysates.

eIF2β (D-3) - sc-133209 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
eIF2β (D-3): sc-133209. Western blot analysis of eIF2β expression in 293 (A), KNRK (B), A-431 (C) and NIH/3T3 (D) whole cell lysates.

eIF2β (C-9) - sc-136972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
eIF2β (C-9): sc-136972. Western blot analysis of eIF2β expression in KNRK (A) and NIH/3T3 (B) whole cell lysates.

eIF2β (E-4) - sc-166536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
eIF2β (E-4): sc-166536. Western blot analysis of eIF2β expression in NIH/3T3 whole cell lysate.

eIF2β (N-13) - sc-31886 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
eIF2β (N-13): sc-31886. Western blot analysis of eIF2β expression in KNRK (A), Jurkat (B), K-562 (C) and NIH/3T3 (D) whole cell lysates.

eIF2β (H-203) - sc-28851 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
eIF2β (H-203): sc-28851. Western blot analysis of eIF2β expression in KNRK (A), HeLa (B), Jurkat (C), K-562 (D), A-431 (E) and NIH/3T3 (F) whole cell lysates.

eIF2β (P-3) - sc-9978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
eIF2β (P-3): sc-9978. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vulva/anal skin tissue showing cytoplasmic staining of epidermal cells.

Anti-EIF2S2 antibody - ab155649 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EIF2S2 antibody (ab155649) at 1/1000 dilution + mouse liver lysate at 50 µg

Anti-EIF2S2 antibody - ab86105 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling EIF2S2 with ab86105 at 1/1000 (1µg/ml). Detection: DAB.

Anti-EIF2S2 antibody - ab77784 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-EIF2S2 antibody (ab77784) at 1/500 dilution + immunogen at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/5000 dilution

Anti-EIF2S2 antibody - ab74836 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EIF2S2 antibody (ab74836) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-EIF2S2 antibody - ab111028 from Abcam

Prices $428.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab111028 at 1/250 dilution staining EIF2S2 in Human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

Anti-EIF2S2 antibody [EPR15833(B)] - ab184549 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15833(B)
Immunofluorescent staining of 4% paraformaldehyde fixed HeLa cells labeling EIF2S2 using ab184549 at a 1/500 dilution and Goat anti rabbit IgG (Alexa Fluor® 555) secondary at a 1/200 dilution, counterstained with Dapi.

Anti-EIF2S2 Antibody (aa270-299, APC) - LS-C213719 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa270-299, Biotin) - LS-C213721 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (phospho-Ser2) - LS-C205087 from LifeSpan Bioscience

Prices $285.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of extracts from C2C12 cells untreated or treated with PMA using eIF2b (phospho-Ser2) antibody.

Anti-EIF2S2 Antibody (aa270-299, Azide-free, HRP) - LS-C213722 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa270-299, FITC) - LS-C213723 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa270-299) - LS-C157707 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
EIF2S2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The EIF2S2 antibody detected the EIF2S2 protein (arrow).

Anti-EIF2S2 Antibody (aa270-299, PE) - LS-C213724 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa75-125) - LS-C288521 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa53-102) - LS-C291919 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody (aa270-299) - LS-C321061 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S2 Antibody - LS-C155267 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca, using EIF2 beta antibody at 1:500 dilution.
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