Gene Symbol |
ELAC1
|
Entrez Gene |
55520
|
Alt Symbol |
D29
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
elaC ribonuclease Z 1
|
Other Description |
RNase Z 1|RNaseZ(S)|deleted in Ma29|elaC homolog 1|elaC homolog protein 1|ribonuclease Z 1|tRNA 3 endonuclease 1|tRNA 3' processing endoribonuclease|tRNA Z (short form)|tRNase Z 1|tRNase ZS|zinc phosphodiesterase ELAC protein 1
|
Swissprots |
Q9H777 Q9NS99
|
Accessions |
EAW62983 EAW62984 Q9H777 AB029151 BAA96799 AF308695 AAG24917 AI870985 AK024822 BAB15021 AK223507 BAD97227 AK310911 BC014624 AAH14624 DQ892785 ABM83711 DQ896032 ABM87031 NM_018696 NP_061166
|
Function |
Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
|
Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:21593607}. Nucleus {ECO:0000269|PubMed:21593607}. Note=Mainly cytosolic.
|
Tissue Specificity |
Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11401430}.
|
Top Pathways |
RNA transport
|