| Gene Symbol |
ELAC1
|
| Entrez Gene |
55520
|
| Alt Symbol |
D29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
elaC ribonuclease Z 1
|
| Other Description |
RNase Z 1|RNaseZ(S)|deleted in Ma29|elaC homolog 1|elaC homolog protein 1|ribonuclease Z 1|tRNA 3 endonuclease 1|tRNA 3' processing endoribonuclease|tRNA Z (short form)|tRNase Z 1|tRNase ZS|zinc phosphodiesterase ELAC protein 1
|
| Swissprots |
Q9H777 Q9NS99
|
| Accessions |
EAW62983 EAW62984 Q9H777 AB029151 BAA96799 AF308695 AAG24917 AI870985 AK024822 BAB15021 AK223507 BAD97227 AK310911 BC014624 AAH14624 DQ892785 ABM83711 DQ896032 ABM87031 NM_018696 NP_061166
|
| Function |
Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:21593607}. Nucleus {ECO:0000269|PubMed:21593607}. Note=Mainly cytosolic.
|
| Tissue Specificity |
Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11401430}.
|
| Top Pathways |
RNA transport
|
![Western Blot: ELAC1 Overexpression Lysate (Adult Normal) [NBL1-10222] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ELAC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2685_ELAC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10222-img0002.jpg)