| Gene Symbol | OVOL2 |
|---|---|
| Entrez Gene | 58495 |
| Alt Symbol | EUROIMAGE566589, ZNF339 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ovo-like zinc finger 2 |
| Other Description | transcription factor Ovo-like 2|zinc finger protein 339 |
| Swissprots | Q9Y4M0 Q9BX22 Q5T8B4 Q9BRP0 Q9HA54 |
| Accessions | EAX10258 EAX10259 Q9BRP0 AI811832 AK022284 BAB14002 AL079276 CAB45151 BC006148 AAH06148 BE791524 BM563561 BT007295 AAP35959 BX331154 DB460914 NM_001303461 NP_001290390 NM_001303462 NP_001290391 NM_021220 NP_067043 |
| Function | Zinc-finger transcription repressor factor. Plays a critical role to maintain the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition mainly through the up-regulation of ZEB1 expression. Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1. {ECO:0000250, ECO:0000269|PubMed:19700410}. |
| Subcellular Location | Nucleus {ECO:0000250}. |
| Tissue Specificity | Expressed in testis, ovary, heart and skeletal muscle. {ECO:0000269|PubMed:12213202}. |
ovo-like 2 (Drosophila) , ELISA Kit - MBS9317661 from MyBioSource
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Human OVOL2 ELISA Kit - E027949 from Biobool
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