HCN1

Gene Symbol HCN1
Entrez Gene 348980
Alt Symbol BCNG-1, BCNG1, EIEE24, HAC-2
Species Human
Gene Type protein-coding
Description hyperpolarization activated cyclic nucleotide gated potassium channel 1
Other Description brain cyclic nucleotide gated channel 1|brain cyclic nucleotide-gated channel 1|hyperpolarization activated cyclic nucleotide-gated potassium channel 1|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Swissprots O60741
Accessions CCF23297 EAW56077 EAW56078 O60741 AF064876 AAC39759 AF488549 AAO49469 AK094523 BC156454 AAI56455 BC172530 AAI72530 BM931647 BX537747 CK299850 DR003732 NM_021072 NP_066550
Function Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli. {ECO:0000269|PubMed:15351778}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15351778}; Multi-pass membrane protein {ECO:0000269|PubMed:15351778}.
Tissue Specificity Detected in brain, in particular in amygdala and hippocampus, while expression in caudate nucleus, corpus callosum, substantia nigra, subthalamic nucleus and thalamus is very low or not detectable. Detected at very low levels in muscle and pancreas. {ECO:0000269|PubMed:9630217}.

HCN1 (V-17) - sc-19706 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HCN1 (V-17): sc-19706. Western blot analysis of HCN1 expression in mouse brain tissue extract.

Anti-HCN1 antibody - ab65706 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-HCN1 antibody (ab65706) at 1/500 dilution + Rat Hippocampus Tissue Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HCN1 antibody - ab19405 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of ab19405 staining in Human hippocampus formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab19405, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-HCN1 antibody - ab176304 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HCN1 antibody (ab176304) at 1/500 dilutionLane 1 : U251 cell lysateLane 2 : Mouse brain lysate

Anti-HCN1 antibody - ab192516 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HCN1 antibody [S70-28] - ab84816 from Abcam

Prices $391.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28
ab84816 staining HCN1 in human hippocampal tissue by IHC-P (Bouin's fixed paraffin embedded).

Anti-HCN1 antibody [S70-28] - C-terminal - ab183408 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 antibody [S70-28] - C-terminal - ab183409 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 antibody [S70-28] - C-terminal - ab183410 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 antibody - Cytoplasmic domain - ab81404 from Abcam

Host Sheep
Clonality Polyclonal

Anti-HCN1 Antibody (aa860-889) - LS-C166816 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HCN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-HCN1 Antibody - LS-C332305 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human thyroid cancer tissue using HCN1 antibody.

Anti-HCN1 Antibody (aa618-890) - LS-C344062 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HCN1 antibody Western blot. All lanes: Anti HCN1 at 0.5 ug/ml. Lane 1: Rat Brain Tissue Lysate at 50 ug. Lane 2: Mouse Brain Tissue Lysate at 50 ug. Lane 3: HELA Whole Cell Lysate at 40 ug. Lane 4: U87 Whole Cell Lysate at 40 ug. Lane 5: MCF-7 Whole Cell Lysate at 40 ug. Predicted band size: 99 kD. Observed band size: 99 kD.

Anti-HCN1 Antibody (N-Terminus) - LS-C7338 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HCN1 Antibody - LS-C94209 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-HCN1 Antibody (C-Terminus) - LS-C123681 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HCN3 Antibody (C-Terminus) - LS-C123682 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HCN1 Antibody - LS-C15642 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HCN1 Antibody (C-Terminus) - LS-C123680 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HCN1 Antibody (C-Terminus) - LS-C144778 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HCN1 Antibody - LS-C154763 from LifeSpan Bioscience

Prices $295.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HCN1 Antibody (aa778-910, clone S70-28, Atto 390) - LS-C227591 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 Antibody (aa778-910, clone S70-28, Atto 633) - LS-C227593 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 Antibody (aa778-910, clone S70-28, Atto 655) - LS-C227594 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28

Anti-HCN1 Antibody (aa778-910, clone S70-28, Atto 594) - LS-C227592 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S70-28
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