HCN1

Gene Symbol HCN1
Entrez Gene 348980
Alt Symbol BCNG-1, BCNG1, EIEE24, HAC-2
Species Human
Gene Type protein-coding
Description hyperpolarization activated cyclic nucleotide gated potassium channel 1
Other Description brain cyclic nucleotide gated channel 1|brain cyclic nucleotide-gated channel 1|hyperpolarization activated cyclic nucleotide-gated potassium channel 1|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Swissprots O60741
Accessions CCF23297 EAW56077 EAW56078 O60741 AF064876 AAC39759 AF488549 AAO49469 AK094523 BC156454 AAI56455 BC172530 AAI72530 BM931647 BX537747 CK299850 DR003732 NM_021072 NP_066550
Function Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli. {ECO:0000269|PubMed:15351778}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15351778}; Multi-pass membrane protein {ECO:0000269|PubMed:15351778}.
Tissue Specificity Detected in brain, in particular in amygdala and hippocampus, while expression in caudate nucleus, corpus callosum, substantia nigra, subthalamic nucleus and thalamus is very low or not detectable. Detected at very low levels in muscle and pancreas. {ECO:0000269|PubMed:9630217}.

HCN1 CRISPR/Cas9 KO Plasmid (h) - sc-404539 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 HDR Plasmid (h) - sc-404539-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 Double Nickase Plasmid (h) - sc-404539-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 Double Nickase Plasmid (h2) - sc-404539-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 CRISPR Activation Plasmid (h) - sc-404539-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 CRISPR Activation Plasmid (h2) - sc-404539-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 Lentiviral Activation Particles (h) - sc-404539-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 Lentiviral Activation Particles (h2) - sc-404539-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCN1 siRNA (h) - sc-44341 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCN1 shRNA Plasmid (h) - sc-44341-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCN1 shRNA (h) Lentiviral Particles - sc-44341-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCN1 RNAi - H00348980-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU019751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9924 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9924 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11669 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11669

HCN1 siRNA (Human) - CRJ7545 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HCN1 - MBS8233452 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HCN1 (NM_021072.3) - SHH310821 from Creative biogene

Category siRNA
Species Reactivities Human

HCN1 shRNA Plasmid (Human) - CHJ7545 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HCN1 miRNA 3'UTR clone - MiUTR4H-TG04108 from Creative biogene

Species Reactivities Human
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